Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | NCI_PDGFR-BETA SIGNALING PATHWAY |
| Enrichment Score (ES) | -0.7617622 |
| Normalized Enrichment Score (NES) | -1.7332063 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008147301 |
| FWER p-Value | 0.047 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | BCAR1 | 18741 | 2225 | 1.277 | -0.0998 | No | ||
| 2 | HRAS | 4868 | 2610 | 0.906 | -0.1063 | No | ||
| 3 | SLC9A3R2 | 23089 1544 1514 | 3024 | 0.543 | -0.1200 | No | ||
| 4 | SHC1 | 9813 9812 5430 | 3936 | 0.225 | -0.1656 | No | ||
| 5 | AKT1 | 8568 | 4218 | 0.183 | -0.1778 | No | ||
| 6 | FYN | 3375 3395 20052 | 5072 | 0.109 | -0.2221 | No | ||
| 7 | SNX15 | 23993 3761 | 5222 | 0.100 | -0.2285 | No | ||
| 8 | SPHK1 | 5484 1266 1402 | 5473 | 0.088 | -0.2406 | No | ||
| 9 | SRC | 5507 | 5727 | 0.076 | -0.2531 | No | ||
| 10 | STAT5B | 20222 | 7325 | 0.036 | -0.3385 | No | ||
| 11 | SHB | 10493 | 7714 | 0.029 | -0.3590 | No | ||
| 12 | HIF1A | 4850 | 7746 | 0.029 | -0.3602 | No | ||
| 13 | NCK1 | 9447 5152 | 7819 | 0.028 | -0.3636 | No | ||
| 14 | GRB10 | 4799 | 8036 | 0.024 | -0.3749 | No | ||
| 15 | PDGFB | 22199 2311 | 8207 | 0.022 | -0.3837 | No | ||
| 16 | PTPN2 | 23414 | 8306 | 0.020 | -0.3887 | No | ||
| 17 | ACP1 | 4317 | 9230 | 0.009 | -0.4382 | No | ||
| 18 | PTPN11 | 5326 16391 9660 | 9360 | 0.007 | -0.4451 | No | ||
| 19 | LYN | 16281 | 10463 | -0.007 | -0.5043 | No | ||
| 20 | YES1 | 5930 | 10960 | -0.014 | -0.5308 | No | ||
| 21 | LRP1 | 9284 | 11848 | -0.027 | -0.5782 | No | ||
| 22 | DOK1 | 17104 1018 1177 | 12045 | -0.031 | -0.5882 | No | ||
| 23 | PIK3R1 | 3170 | 12502 | -0.041 | -0.6122 | No | ||
| 24 | PLCG1 | 14753 | 12675 | -0.046 | -0.6207 | No | ||
| 25 | SOS1 | 5476 | 13046 | -0.056 | -0.6398 | No | ||
| 26 | PDGFRB | 23539 | 13453 | -0.070 | -0.6605 | No | ||
| 27 | PIK3CA | 9562 | 13540 | -0.075 | -0.6640 | No | ||
| 28 | ABL1 | 2693 4301 2794 | 14050 | -0.106 | -0.6897 | No | ||
| 29 | GRB7 | 20673 | 14124 | -0.112 | -0.6919 | No | ||
| 30 | CBL | 19154 | 14602 | -0.166 | -0.7150 | No | ||
| 31 | VAV2 | 5848 2670 | 14978 | -0.236 | -0.7315 | No | ||
| 32 | STAT5A | 20664 | 15113 | -0.268 | -0.7345 | No | ||
| 33 | MYC | 22465 9435 | 15334 | -0.330 | -0.7412 | No | ||
| 34 | LCK | 15746 | 15440 | -0.368 | -0.7411 | No | ||
| 35 | FGR | 4723 | 15758 | -0.526 | -0.7499 | No | ||
| 36 | HCK | 14787 | 15979 | -0.695 | -0.7509 | Yes | ||
| 37 | PTPN1 | 5325 | 16168 | -0.897 | -0.7469 | Yes | ||
| 38 | PTPRJ | 9664 | 16387 | -1.089 | -0.7416 | Yes | ||
| 39 | NCK2 | 9448 | 16530 | -1.250 | -0.7296 | Yes | ||
| 40 | RAC1 | 16302 | 16651 | -1.434 | -0.7136 | Yes | ||
| 41 | RASA1 | 10174 | 16815 | -1.689 | -0.6959 | Yes | ||
| 42 | PRKCD | 21897 | 17290 | -2.395 | -0.6839 | Yes | ||
| 43 | GRB2 | 20149 | 17590 | -3.055 | -0.6521 | Yes | ||
| 44 | SLC9A3R1 | 11250 | 17768 | -3.541 | -0.6061 | Yes | ||
| 45 | PTEN | 5305 | 18200 | -4.996 | -0.5509 | Yes | ||
| 46 | GAB1 | 18828 | 18283 | -5.430 | -0.4702 | Yes | ||
| 47 | STAT1 | 3936 5524 | 18294 | -5.505 | -0.3844 | Yes | ||
| 48 | CSK | 8805 | 18359 | -5.871 | -0.2958 | Yes | ||
| 49 | BLK | 3205 21791 | 18378 | -5.983 | -0.2029 | Yes | ||
| 50 | STAT3 | 5525 9906 | 18455 | -6.760 | -0.1010 | Yes | ||
| 51 | DNM2 | 4635 3103 | 18471 | -6.991 | 0.0078 | Yes |
